This Special Issue is dedicated to building a bridge between different disciplines concerned in the investigation of the qualitative dimension of experience and reality. The two main objectives of the Issue can be summarized as follows:

• to elucidate the need for a revision of categories to account for the qualitative dimension in various disciplines (that include, for example, the cognitive sciences, neurosciences, biology, linguistics, informatics, artificial intelligence, robotics, newly emerging computer technologies) in order to develop an ontology that can better account for the qualitative, dynamic and relational aspects of different domains of reality;
• to explore the implications of the enactivist view for a relational and ecological account of the qualitative dimensions of life and cognition;