“The revolution in thinking brought about by quantum mechanics was profound, and its implications are still being explored in such phenomena as entanglement and decoherence. I’m not sure I agree with your analogy, because it equates quantum indeterminacy with a more general epistemological limit on the nature of knowledge, but we should remember that quantum effects become negligible (although still present) at macroscale levels. I tend to favour Karen Barad’s take on this in her notion of “agential realism,” in which she argues that the experimental apparatus is part of what determines the kinds of observations that a given experiment will yield (a point she develops from the philosophy of Niels Bohr). From here she makes a leap into ontology, arguing that reality itself is brought into being by intra-actions between agents; without these intra-actions (which might be between subatomic particles, between particles and instruments such as those at CERN, or between humans, instruments, and particles), reality could not exist. Hence the point is not so much a limit to our ability to know the world, but rather our active participation, along with myriad other agents, in bringing the world into being as such.” – See more at: http://twentythree.fibreculturejournal.org/fcj-172-posthumanism-technogenesis-and-digital-technologies-a-conversation-with-katherine-n-hayles